Whitening Gold-Glabridin

Glabridin is a kind of flavonoids extracted from a precious plant called licorice. Glabridin is known as "whitening gold" because of its powerful whitening effect, which can eliminate free radicals and melanin at the bottom of the muscle. It is a skin whitening and anti-aging holy artifact.
Properties: The low content of this product is brown powder, and the high content is white powder.
Solubility: Insoluble in water, soluble in organic solvents, care must be taken when preparing.

Applications:
 

1. Cosmetic industry
Extracted from the root of Glycyrrhiza glabra L. (syn. Liquiritae officinalis Moench., Fani. Fabaccae), used as a cosmetic raw material.
Licorice is one of the most widely used herbs in the world, and in Ayurvedic medicine it can aid in the treatment of eye diseases, throat infections, stomach ulcers, arthritis and liver disease. The reason is that it is expectorant, emollient, anti-inflammatory, anti-filtering pathogens, anti-hepatotoxic and anti-bacterial.
 

2.Flavonoids
Glycyrrhiza (whitening gold) \ (licorice whitening essence PT-40) can penetrate deep into the skin and maintain high activity, whitening and high-efficiency antioxidant. Effectively inhibit the activity of various enzymes in the process of melanin production, especially inhibit the activity of tyrosinase. At the same time, it also has the effect of preventing rough skin and anti-inflammatory and antibacterial. Glycyrrhiza glabra is a whitening ingredient with good curative effect and comprehensive functions. Glycyrrhiza glabra is a whitening cosmetic additive introduced by Japan's MARUZEN Company in 1989. After years of use, the effect is obvious and the safety is good. It is the main functional ingredient of high-end whitening cosmetics in the world.
Glycyrrhizapine in cosmetic applications: 1. Whitening, inhibiting melaninogen; 2. Anti-inflammatory; 3. Antioxidant.

Glycyrrhizin, a hydrophobic component in licorice extract, has a very good anti-inflammatory and whitening effect. Glycyrrhizin and glycyrrhizic acid also have anti-inflammatory properties. These hydrophobic components are licorice and other flavonoids, which have the effect of inhibiting melanin. In vivo and in vitro experiments have been done on the activity of licorice in inhibiting melanin production.

3. Other effects
Glycyrrhizin significantly reduces hyperpigmentation caused by UV exposure, and a histological study of the skin at the site of application has also been performed. The use of licorice can also increase the radiance of the skin. The researchers concluded that licorice root in licorice root not only inhibits melanin formation, but is also anti-inflammatory.
The main mechanism of action of glabridin to inhibit melanin is as follows:

3.1 Inhibit tyrosinase
Human tyrosinase is an essential enzyme that regularly produces melanin, which turns the skin or eyes from brown to black. Active oxygen is a substance that can cause skin pigmentation, so inhibiting its production can inhibit the production of melanin. Glycyrrhizin is the most expensive and most effective whitening ingredient among all whitening ingredients. According to "Ben Cao Zhonghua", the whitening effect of Glycyrrhizin is 232 times that of ordinary vitamin C and 16 times higher than that of hydroquinone. "Arbutin "1164 times, so licorice is called "whitening gold".

3.2 Inhibit tyrosinase
Human tyrosinase is an essential enzyme that regularly produces melanin, which turns the skin or eyes from brown to black. Active oxygen is a substance that can cause skin pigmentation, so inhibiting its production can inhibit the production of melanin. Glycyrrhizin is the most expensive and The most effective whitening ingredient among all whitening ingredients. According to "Ben Cao Zhonghua", the whitening effect of Glycyrrhizin is 232 times that of ordinary vitamin C and 16 times higher than that of hydroquinone. "Arbutin "1164 times, so licorice is called " whitening gold".

3.3 Anti-oxidize effect
Glycyrrhiza has a strong scavenging effect on free radicals. Vitamin C, vitamin E and β-carotene are recognized as the three kings of anti-oxidation and anti-aging. It is reported that the antioxidant effect of its antioxidants is significantly better than that of BHA and BHT. It has been reported in the literature that licorice can be used to reduce corticosteroids in infectious skin diseases and can enhance the effect of steroids.

4. Cosmetic application
Glycyrrhizin has excellent anti-inflammatory, antioxidant and anti-melanin formation properties, so it is used as an ingredient in various cosmetic and medical care products such as creams, lotions, body washes, etc. It can be made into a whitening cream.
The phospholipid bilayer membrane of glabridin liposome is similar to biological membrane, and it is easy to fuse with organisms, which promotes the penetration of functional components to biological membranes, and makes the efficiency of functional components trans-skin barrier and biological membrane transport higher. It has a positive effect on improving its skin whitening and freckle-removing effect and other auxiliary effects.