PDRN + 400Da Hyaluronic Acid: The Golden Combination of Anti-aging Repair and Deep Hydration

In modern skincare, consumers increasingly seek active ingredients that deliver significant anti-aging effects without irritating the skin. Among today's most sought-after active ingredients, PDRN and 400Da hyaluronic acid stand out for their exceptional performance in skin repair, deep hydration, and regeneration. Using them together creates a highly effective combination to achieve long-term anti-aging goals.
 

Why PDRN Has Become a Popular Anti-aging Ingredient
 

PDRN (polydeoxynucleotide) is widely recognized for its outstanding skin regeneration capabilities. Originally used in medical repair treatments, PDRN's nucleotide sequence is highly similar to human DNA, exhibiting excellent biocompatibility, and has become a popular anti-aging skincare ingredient.

Its main anti-aging effects include:
Enhancing skin's repair and recovery capabilities
Improving skin firmness and elasticity
Caring for fragile or sensitive skin
Reducing fine lines and dullness

400Da Hyaluronic Acid: Deep Molecular-Level Hydration

Compared to traditional hyaluronic acid, 400Da hyaluronic acid is an ultra-low molecular weight form that can penetrate deep into the epidermis. This deeper penetration delivers long-lasting hydration, smoother skin texture, and better water-oil balance. (Focusfreda is one of the few manufacturers worldwide that provides 400Da hyaluronic acid.)

Main moisturizing effects:
Deeply moisturizes dry skin
Strengthens the skin barrier and improves skin elasticity
Promotes the absorption of other active ingredients
Repairs AQP3 gene expression after UV damage
Increases aquaporin content

Synergistic effect: Anti-aging + Repair + Hydration
 

The combination of PDRN and 400Da hyaluronic acid produces dual benefits, which is crucial for anti-aging skincare:

Regeneration + Deep Hydration: PDRN promotes skin repair, while 400Da hyaluronic acid deeply hydrates.
Strengthens the skin barrier: Hydrated skin responds more effectively to PDRN regeneration signals.
Significant anti-aging effects: Users can immediately experience improved skin smoothness and long-term firmness.

Who benefits most?
 

This combination is especially suitable for:
Anti-aging and early wrinkles
Dry, tight, or dehydrated skin
Sensitive or over-treated skin
Skin requiring long-term repair
 

Conclusion
 

With the increasing demand for highly effective anti-aging skincare products, the combination of PDRN and 400Da hyaluronic acid provides a powerful scientific solution. It deeply moisturizes and repairs the skin, offering an effective strategy for creating smoother, firmer, and more elastic skin.

About Focusfreda
 

Focusfreda, a subsidiary of Lushang Freda Pharmaceutical Co., Ltd., has grown into a global supplier specializing in the research and production of high-purity sodium hyaluronate for pharmaceuticals, cosmetics, and nutritional supplements. With 30 years of professional manufacturing experience and advanced cleanroom facilities, we are committed to sustainable development, safe production, and consistent quality, earning the trust of numerous top pharmaceutical and beauty brands.

PDRN is supplied by a partner factory and is supplied together with sodium hyaluronate.