Collagen Product

Collagen is a biopolymer, the main component of animal connective tissue, and the most abundant and widely distributed functional protein in mammals, accounting for 25% to 30% of the total protein, and even as high as 80% in some organisms. 
Animal tissue derived from livestock and poultry is the main way for people to obtain natural collagen and its collagen peptides. However, due to related animal diseases and certain religious beliefs, people's use of terrestrial mammalian collagen and its products is limited, and now it is gradually turning to the ocean. developed in biology. The European Food Safety Authority (EFSA) has confirmed that even collagen derived from animal bones does not have the potential to contract mad cow disease and other related diseases.

Due to the differences in amino acid composition and degree of cross-linking, the rich collagen contained in the skin, bones and scales of aquatic animals, especially their processing wastes, has many advantages that livestock collagen does not have. In addition, it comes from the ocean. Animal collagen is obviously superior to terrestrial collagen in some aspects, such as low antigenicity and hypoallergenicity. Therefore, aquatic collagen may gradually replace terrestrial animal collagen.
There are many types of collagen, and the common types are type I, type II, type III, type V and type XI.
Collagen has been widely used in food, medicine, tissue engineering, cosmetics and other fields because of its good biocompatibility, biodegradability and biological activity.
 

Pharmaceutical industry 

(1) Biomedical materials
(2) Human tissue
(3) Skin

Cosmetic
1. Collagen is extracted from animal skin. In addition to collagen, the skin also contains proteoglycans such as hyaluronic acid and chondroitin sulfate. They contain a large number of polar groups, which are moisturizing factors and prevent the conversion of tyrosine in the skin. Because of the role of melanin, collagen has the functions of pure natural moisturizing, whitening, anti-wrinkle, freckle removal, etc., and can be widely used in beauty products. The chemical composition and structure of collagen gives it the foundation of beauty. Collagen is similar in structure to human skin collagen. It is a non-water-soluble fibrous sugar-containing protein. The molecule is rich in a large number of amino acids and hydrophilic groups. It has certain surface activity and good compatibility. A lot of hydroxyl, so it has a pretty good moisturizing effect.

2. With the increase of age, the synthesis ability of fibroblasts decreases. If there is a lack of collagen in the skin, the collagen fibers will be solidified, which will reduce the intercellular mucopolysaccharide, and the skin will lose its softness, elasticity and luster, and aging will occur. At the same time, the fibers of the dermis are broken, fat atrophy, the secretion of sweat glands and sebaceous glands are reduced, and a series of aging phenomena such as pigmentation and wrinkles appear on the skin. When it is used as an active substance in cosmetics, the latter can diffuse into the deep layers of the skin, and the tyrosine contained in it competes with the tyrosine in the skin and binds to the catalytic center of tyrosinase, thereby inhibiting the production of melanin. It can enhance the activity of collagen in the skin, maintain the moisture of the stratum corneum and the integrity of the fiber structure, promote the metabolism of the skin tissue, and have a good moisturizing, moisturizing, wrinkle-reducing and cosmetic effect on the skin.

3. However, in cosmetics, it is usually required that the molecular weight is below 2KDa, so that the hydrolyzed collagen can penetrate into the skin. In addition to the moisturizing properties of hydrolyzed collagen, hair care cosmetics should also have certain film-forming properties. Therefore, the molecular weight of hydrolyzed collagen will be higher.

Food Grade

Collagen can also be used in food, and for a long time, some products containing collagen have been considered to be very beneficial to joints. Because it has some properties suitable for food:
Food grade is usually white in appearance, soft in taste, light in taste and easy to digest. It can reduce blood triglyceride and cholesterol, and can increase some essential trace elements that are lacking in the body to maintain them within a relatively normal range. It is an ideal hypolipidemic food.
In addition, studies have shown that collagen can help eliminate aluminum in the body, reduce the aggregation of aluminum in the body, reduce the harm of aluminum to the human body, and promote the growth of nails and hair to a certain extent.
Type II collagen is the major protein in articular cartilage and is therefore a potential autoantigen. After oral administration, T cells can induce immune tolerance, thereby inhibiting T cell-mediated autoimmune diseases.

Health products
Collagen is an important component of human bones, especially cartilage tissue. The characteristic amino acid of collagen, hydroxyproline, is a tool in the plasma to transport calcium to bone cells. Collagen in bone cells is a binder for hydroxyapatite, which together with hydroxyapatite constitutes the main body of bones. The rate of new collagen production is lower than the rate at which old collagen mutates or ages. Studies have shown that if there is a lack of collagen, no amount of calcium supplementation can prevent osteoporosis. Therefore, only by ingesting enough collagen that can be combined with calcium can calcium be digested and absorbed faster in the body, and it can be more quickly digested and absorbed. Quickly reach the bone site and deposit.

Feed
It has better feeding effect and economic benefits. It has high protein content, is rich in more than 18 kinds of amino acids, contains calcium, phosphorus, iron, manganese, selenium and other mineral elements, and has an aromatic flavor.
Collagen has a high rate of digestion and absorption, and can partially replace fish meal without affecting the weight gain of fish.
Other
Copper deficiency can be predicted; hepatic fibrosis can also be predicted by measuring the amount of collagen in the liver because hepatic fibrosis reduces protein content. Collagen is also the main component of the sclera, and it is also very important for the eyes. If the synthesis of collagen in the sclera decreases and the degradation increases, it will lead to myopia.

Due to the differences in amino acid composition and degree of cross-linking, the rich collagen contained in the skin, bones and scales of aquatic animals, especially their processing wastes, has many advantages that livestock collagen does not have. In addition, it comes from the ocean. Animal collagen is obviously superior to terrestrial collagen in some aspects, such as low antigenicity and hypoallergenicity. Therefore, aquatic collagen may gradually replace terrestrial animal collagen.
There are many types of collagen, and the common types are type I, type II, type III, type V and type XI.
Collagen has been widely used in food, medicine, tissue engineering, cosmetics and other fields because of its good biocompatibility, biodegradability and biological activity.
 

Pharmaceutical industry 

(1) Biomedical materials
(2) Human tissue
(3) Skin

Cosmetic
1. Collagen is extracted from animal skin. In addition to collagen, the skin also contains proteoglycans such as hyaluronic acid and chondroitin sulfate. They contain a large number of polar groups, which are moisturizing factors and prevent the conversion of tyrosine in the skin. Because of the role of melanin, collagen has the functions of pure natural moisturizing, whitening, anti-wrinkle, freckle removal, etc., and can be widely used in beauty products. The chemical composition and structure of collagen gives it the foundation of beauty. Collagen is similar in structure to human skin collagen. It is a non-water-soluble fibrous sugar-containing protein. The molecule is rich in a large number of amino acids and hydrophilic groups. It has certain surface activity and good compatibility. A lot of hydroxyl, so it has a pretty good moisturizing effect.

2. With the increase of age, the synthesis ability of fibroblasts decreases. If there is a lack of collagen in the skin, the collagen fibers will be solidified, which will reduce the intercellular mucopolysaccharide, and the skin will lose its softness, elasticity and luster, and aging will occur. At the same time, the fibers of the dermis are broken, fat atrophy, the secretion of sweat glands and sebaceous glands are reduced, and a series of aging phenomena such as pigmentation and wrinkles appear on the skin. When it is used as an active substance in cosmetics, the latter can diffuse into the deep layers of the skin, and the tyrosine contained in it competes with the tyrosine in the skin and binds to the catalytic center of tyrosinase, thereby inhibiting the production of melanin. It can enhance the activity of collagen in the skin, maintain the moisture of the stratum corneum and the integrity of the fiber structure, promote the metabolism of the skin tissue, and have a good moisturizing, moisturizing, wrinkle-reducing and cosmetic effect on the skin.

3. However, in cosmetics, it is usually required that the molecular weight is below 2KDa, so that the hydrolyzed collagen can penetrate into the skin. In addition to the moisturizing properties of hydrolyzed collagen, hair care cosmetics should also have certain film-forming properties. Therefore, the molecular weight of hydrolyzed collagen will be higher.

Food Grade

Collagen can also be used in food, and for a long time, some products containing collagen have been considered to be very beneficial to joints. Because it has some properties suitable for food:
Food grade is usually white in appearance, soft in taste, light in taste and easy to digest. It can reduce blood triglyceride and cholesterol, and can increase some essential trace elements that are lacking in the body to maintain them within a relatively normal range. It is an ideal hypolipidemic food.
In addition, studies have shown that collagen can help eliminate aluminum in the body, reduce the aggregation of aluminum in the body, reduce the harm of aluminum to the human body, and promote the growth of nails and hair to a certain extent.
Type II collagen is the major protein in articular cartilage and is therefore a potential autoantigen. After oral administration, T cells can induce immune tolerance, thereby inhibiting T cell-mediated autoimmune diseases.

Health products
Collagen is an important component of human bones, especially cartilage tissue. The characteristic amino acid of collagen, hydroxyproline, is a tool in the plasma to transport calcium to bone cells. Collagen in bone cells is a binder for hydroxyapatite, which together with hydroxyapatite constitutes the main body of bones. The rate of new collagen production is lower than the rate at which old collagen mutates or ages. Studies have shown that if there is a lack of collagen, no amount of calcium supplementation can prevent osteoporosis. Therefore, only by ingesting enough collagen that can be combined with calcium can calcium be digested and absorbed faster in the body, and it can be more quickly digested and absorbed. Quickly reach the bone site and deposit.

Feed
It has better feeding effect and economic benefits. It has high protein content, is rich in more than 18 kinds of amino acids, contains calcium, phosphorus, iron, manganese, selenium and other mineral elements, and has an aromatic flavor.
Collagen has a high rate of digestion and absorption, and can partially replace fish meal without affecting the weight gain of fish.
Other
Copper deficiency can be predicted; hepatic fibrosis can also be predicted by measuring the amount of collagen in the liver because hepatic fibrosis reduces protein content. Collagen is also the main component of the sclera, and it is also very important for the eyes. If the synthesis of collagen in the sclera decreases and the degradation increases, it will lead to myopia.