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Do you know what is Sodium Hyaluronate?

Release time:

2022-06-21


Sodium hyaluronate, with the chemical formula (C14H20NO11Na)n, is an inherent component in the human body. It is widely found in placenta, amniotic fluid, lens, articular cartilage, skin dermis and other tissues and organs. It is distributed in the cytoplasm and intercellular substance, and plays a role in lubricating and nourishing the cells and cellular organs themselves.

 

At the same time, it provides a microenvironment for cell metabolism. It is a kind of gel made by combining a human body's natural "hyaluronic acid" with other anti-wrinkle drugs that promote cell regeneration, and is used by injection.

Moisturizing effect is the most important role of sodium hyaluronate in cosmetics.
 

Principle

The traditional theory holds that the formation of wrinkles is related to the rupture or loss of collagen elastic fibers.

Modern medical research has found that another fundamental reason for the formation of wrinkles is the change of the intercellular substance, that is, the reduction of the formless component "hyaluronic acid" between cells, while the cell scaffold and elastic fibers still exist. Micro plastic surgery is to supplement the lost invisible interstitial components, and then change the metabolic environment of cells and the balance of water and ions, thereby increasing the viscoelasticity of the skin and achieving the cosmetic effect.

Sodium hyaluronate is the main component of synovial fluid in the joint cavity and one of the components of the cartilage matrix. It plays a lubricating role in the joints and reduces the friction between tissues. After injection into the joint cavity, it can significantly improve the inflammatory response of synovial fluid tissue and enhance the The viscosity and lubricating function of synovial fluid can protect articular cartilage, promote the healing and regeneration of articular cartilage, relieve pain and increase joint mobility.
 

Effect

  1. Improve efficacy
  2. Wrinkle resistance
  3. Moisturizing effect
  4. Nutritional effect
  5. Repair and Prevent
  6. Lubrication and Film Formation
  7. Thickening
  8. Pharmacological action

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What are the different effects of different molecular weights of sodium hyaluronate in the treatment of knee osteoarthritis?

Knee osteoarthritis (KOA) is a common chronic joint disease with an increasing prevalence among older adults, severely impacting quality of life. Sodium hyaluronate (SH), as a core component of synovial fluid, is a key drug in KOA treatment. However, different molecular weights of SH exhibit significant differences in efficacy and mechanism of action, directly affecting treatment options. This article focuses on interpreting its differentiating effects to provide a reference for clinical application. [Reference Interpretation: Figure 1]

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